Associated Press photos by Susan Walsh![]() ![]() |
![]() |
![]() |
DR. PATRICIA BERG - BEHIND A BREAST CANCER BREAKTHROUGH
Thursday, April 24, 2003
The discovery of a new breast cancer gene could provide a major breakthrough
in detecting and treating the second leading cause of deaths among women.
Every year more than 200,000 cases of breast cancer are diagnosed and
40,000 people die from the disease.
Dr. Patricia Berg, of the George Washington University, leads the
Medical team responsible for the discovery of the gene. She spoke with 9News
about what her findings mean.
GENE RESEARCH POINTS TO NEW BREAST CANCER TREATMENTS;
FIND OFFERS HOPE FOR EARLIER DETECTION
AND THERAPY TARGETED TO CELLULAR COMPONENTS;
AFRICAN AMERICANS MAY BENEFIT THE MOST
April 24, 2003
Los Angeles Times
WASHINGTON (Reuters) -- Researchers say they have found
a gene linked to breast cancer that could lead to new treatments and help
explain why black women are more likely to die of breast cancer than whites.
The gene, called BP1, was found in 80% of the samples of tissue from breast
cancer patients, the researchers report in the June issue of the journal
Breast Cancer Research.
"We are hoping our results will be especially helpful for
African-American women," said Dr. Patricia Berg of the George Washington
University Medical Center, who led the study.
Although 57% of samples from white breast cancer patients
tested positive for the gene, 89% from black women did, the researchers
said.
"Because BP1 is expressed abnormally in breast tumors, it could
provide a useful target for therapy," Berg's team wrote.
Berg noted that her team tested only 46 samples, but she said
the percentages were consistent. Of the nine normal breast samples she
has tested, only one has shown "expression," or activation, of the BP1
gene. She also tested only ductal cancer -- but ductal cancer makes up
80% of malignant cancers.
Berg said that like some other genes linked with cancer, BP1
was activated early in the development of an embryo and turned off later.
That is known as a transcription factor.
"This type of gene makes a protein that is like a policeman
directing traffic and turns on and turns off other genes," Berg said.
Her team will now try to find out what those other genes are.
Berg earlier found that BP1 was active in leukemia, particularly
a form called acute myeloid leukemia. In AML patients it was found to be
very active in children.
A leukemia drug called all-trans-retinoic acid seemed to deactivate
BP1 in lab dishes, Berg said, showing that there is a potential for a drug
targeting the gene.
"What we want to do is discover whether this gene will be
useful for the early detection and treatment of breast cancer," Berg said.
"We found that the gene is active in all three grades of breast tumors,
from the earliest to the most advanced. That means it is activated quite
early in the process and potentially might be good for early detection."
She said she was working with a colleague to try to develop such a test.
All the estrogen-receptor negative tumors that were studied
tested positive for the BP1 gene, the researchers said.
Breast cancers fall into two categories -- those that respond
to anti-estrogen therapy and those that do not. So-called ER-positive tumors
are easier to treat and respond to such popular drugs as tamoxifen.
ER-negative tumors, which make up 40% of breast cancers, do
not. BP1 thus might offer a new avenue for treating such tumors, Berg's team
said.
Black women in the U.S. are more likely to have ER-negative
tumors, researchers have found. They are also more likely to die of breast
cancer.
More than 200,000 U.S. women will develop breast cancer this
year, and 40,000 will die of the disease in 2003, according to the American
Cancer Society.
WASHINGTON (Reuters) - U.S. researchers said on Tuesday they had found
a new gene linked with breast cancer that could lead to new treatments
and help explain why black women are more likely to die from breast cancer
than whites.
The gene, called BP1, was found in 80 percent of the samples of tissue
from breast cancer patients, the researchers report in the June issue
of the journal Breast Cancer Research.
"We are hoping our results will be especially helpful for African-American
women," Dr. Patricia Berg of the George Washington University Medical Center,
who led the study, said in a telephone interview.
While just 57 percent of samples from white breast cancer patients
tested positive for the gene, 89 percent from black women did, the researchers
said.
"Because BP1 is expressed abnormally in breast tumors, it could provide
a useful target for therapy," Berg's team writes.
Berg noted that her team tested only 46 samples, but she said the
percentages were consistent. Of the nine normal breast samples she has
tested, only one has shown "expression," or activation, of the BP1 gene.
She also only tested ductal cancer -- but ductal cancer makes up 80
percent of breast cancers.
Berg said that like some other genes linked with cancer, BP1 was activated
early in the development of an embryo and turned off later.
The gene activates other genes. It is known as a transcription factor.
"This type of gene makes a protein that is like a policeman directing
traffic and turns on and turns off other genes," she said.
Her team will now try to find out what those other genes are.
In earlier work, Berg had found that BP1 is active in leukemia, particularly
a form called acute myeloid leukemia, or AML. In AML patients, it was
very active in children.
A leukemia drug called all-trans-retinoic acid seemed to deactivate
BP1 in lab dishes, Berg said -- showing there is potential for a drug
targeting the gene.
"What we want to do is discover whether this gene will be useful for
the early detection and treatment of breast cancer," Berg said.
"We found that the gene is active in all three grades of breast tumors,
from the earliest to the most advanced. That means it is activated quite
early in the process and potentially might be good for early detection."
She said she is working with a colleague to try to develop such a test.
In a potential lucky piece of news, all the estrogen receptor-negative
tumors tested positive for the BP1 gene, the researchers said.
Breast cancers fall into two categories -- those that respond to anti-estrogen
therapy and those that do not. So-called ER-positive tumors are easier
to treat and respond to such popular drugs as tamoxifen.
ER-negative tumors, which make up 40 percent of breast cancers, do
not. BP1 might offer a new avenue for treating such tumors, Berg's team
said.
Black women in the United States are more likely to have ER-negative
tumors, researchers have found, and are also more likely to die of breast
cancer even when they get similar treatment to white women.
More than 1.2 million women worldwide will develop breast cancer this
year -- 200,000 in the United States. In the United States, 40,000 will
die of breast cancer in 2003, according to the American Cancer Society.
SUSPECTED BREAST CANCER GENE MORE ACTIVE IN BLACKS
April 21, 2003
The Washington Post
Researchers investigating a gene that they suspect helps spur breast
cancer have found an unusual racial disparity: The gene appears active
more often in the tumors of black women than in those of white women.
Breast cancer isn't as common among black women, yet black patients
are more likely to die of the disease. Only part of the problem is socioeconomic.
The new study of the gene, called BP1, provides a promising lead,
said chief researcher Patricia Berg of George Washington University Medical
Center, whose findings will be published today by the journal Breast Cancer
Research.
Berg first discovered that BP1 was active in many patients with a
type of leukemia. Her research suggested that when the gene is switched
on, it helps cancerous cells survive.
Wondering if BP1 played a role in other malignancies, she tested breast
cancer tissue from 46 patients. Berg found BP1 activity in 89 percent of
the tumors from black women and 57 percent of the white women's tumors.
She found BP1 expression in only one of seven samples of normal breast tissue.
The study also suggests that the gene's effects may occur very early in
the cancer development process, which means it may be useful for early detection.
Other cancer specialists called the findings intriguing but cautioned
that the study was far too small to determine if BP1 really plays a role
in breast cancer, particularly the racial disparity.
"This may be a tip-off, but it's too early to tell," said Herman Kattlove
of the American Cancer Society. Another question is just what role BP1 plays
in overall cancer development, said Joseph Fontana of Wayne State University
-- noting that Berg also found BP1 activity in two benign breast tumors.
-- Associated Press
NEW TUMOR HOPE
by Adam Miller
April 24, 2003
New York Post National News
In a major breakthrough, scientists have discovered a gene
linked to breast cancer that could lead to new treatments and allow the early
detection of the disease, researchers said yesterday.
The findings may also help explain why black women are more likely
to die from the insidious disease than whites.
A team of researchers at George Washington University in D.C.
found a gene, called BP1, in 80 percent of breast-cancer patients they studied.
"We think this is an early significant finding," Dr. Patricia
Berg, the lead researcher and the gene's discoverer, told The Post.
"We think that this gene may offer a potential early target for
breast-cancer detection and therapy. We now must conduct expedited research."
Berg added she hopes the findings will lead to the development
of a blood test that will allow doctors to detect breast cancer early.
"Early detection is the biggest key to increasing survival
rate," said Berg, who has been studying the gene for the past 16 years.
She said the hardest-to-treat breast-cancer tumors turned
out to be the most likely to have the BP1 switched on.
Berg said the findings "may prove especially helpful to African-American
women, who disproportionately expressed the new gene."
Eighty-nine percent of black breast-cancer patients tested
positive for the activation of the gene, compared with 57 percent of whites.
And studies have shown that African-American women are less
likely to survive breast cancer than Caucasian women.
Berg's boss, Dr. Allan Goldstein, hailed the study, saying
that if the findings hold up, "her team has in effect discovered what may
turn out to be the face of the enemy."
"The results are both important and exciting in terms of potential
clinical application," he added.
But Berg, an associate professor of biochemistry and molecular
biology at GWU's School of Medicine and Health Sciences, cautioned the findings
are just the first step, saying other scientists will need to confirm them.
However, she asserted that the discovery, cloning and findings
of the effects of the new gene "could now expedite research to put us further
on the trail of treating breast cancer and other cancers."
The study, of 46 breast-cancer tumors, has been published
in the journal Breast Cancer Research.
Berg said the battle against breast cancer hits close to home.
"As a scientist and as a mother of a daughter, I want to do
something" against the disease, said Berg, who began breast-cancer testing
in 1999.
Breast cancer is the most common form of cancer among women
worldwide.
And it is the leading cause of death among American women between
the ages of 33 and 55.
This year alone, more than 200,000 women in the United States
will develop the disease - and about 40,000 will die from it, according to
the American Cancer Society.
About 375,000 women across the world die of the disease each
year.
The rate of women with breast cancer is increasing about half
a percent a year.
Researchers say they have found a gene linked with breast cancer
that could lead to new treatments and help explain why black women are
more likely to die from breast cancer than white women are.
The gene, called BP1, was found in 80 percent of tissue samples from
breast cancer patients, the researchers reported in the June issue of the
journal Breast Cancer Research.
Dr. Patricia Berg of the George Washington University Medical Center,
who led the study, said that while just 57 percent of samples from white
breast cancer patients tested positive for the gene, 89 percent from black
women did.
WASHINGTON -- Researchers investigating a gene that they
suspect helps spur breast cancer found an unusual racial disparity: The
gene appears active more often in the tumors of black women than white women.
Breast cancer isn't as common among black women as white women,
yet black patients are more likely to die of their disease. Only part of
the problem is socioeconomic. Specialists now agree that breast cancer seems
more aggressive in black women, although they can't explain why.
The new study of the gene called BP1 provides a promising lead,
said chief researcher Dr. Patricia Berg of George Washington University Medical
Center, whose findings will be published Tuesday by the journal Breast
Cancer Research.
Berg first discovered that BP1 was active in numerous patients
with a type of leukemia. Her research suggested that when the gene is switched
on, it interferes with cell regulation in a way that helps cancerous cells
survive.
Wondering if BP1 played a role in other malignancies, she tested
breast cancer tissue from 46 patients. Berg found BP1 activity in 89 percent
of the tumors from black women, compared with 57 percent of the white women's
tumors.
Berg found BP1 expression in only one of seven samples of normal
breast tissue.
Another surprise: BP1 was active in 100 percent of tumors that
are hard to treat because they are not affected by estrogen, compared with
three-fourths of estrogen-sensitive tumors.
Other cancer specialists called the findings intriguing, but
cautioned that the study was far too small to determine if BP1 really plays
a role in breast cancer, particularly the racial disparity.
"This may be a tip-off, but it's too early to tell," said
Dr. Herman Kattlove of the American Cancer Society.
Another question is just what role BP1 plays in overall cancer
development, said Dr. Joseph Fontana of Wayne State University -- noting
that Berg also found BP1 activity in two benign breast tumors.
Berg plans additional testing to see how often BP1 activity
is detected in non-cancerous breast tissue, and is working to develop a
blood test.
Copyright © 2003, The Associated Press
HEIDI COLLINS, CNN ANCHOR: New medical research could have
a big impact on early detection and treatment of breast cancer. A new gene,
called BP1, has been found in preliminary studies to be active in 80 percent
of all breast tumors. What could this mean for the diagnosis and treatment
of the disease? Dr. Patricia Berg is an associate professor of biochemistry
and molecular biology at George Washington University, and a lead researcher
on the gene study. She is in Washington this morning, and joins us now.
Hello to you, doctor.
DR. PATRICIA BERG, GEORGE WASHINGTON UNIVERSITY: Hi, Heidi.
COLLINS: This is an exciting find. Tell us, if you will, what,
indeed, it does mean for diagnosis and then treatment.
BERG: Well as a scientist and the mother of a daughter, I want
to help do something about the 212,000 women in the U.S. that will be diagnosed
with breast cancer this year, and the 40,000 women who will die of the
disease. We have discovered and cloned a new gene called BP1, which we
just found is expressed in 80 percent of breast tumors. This is a very high
number, and we think that that means this gene is a good potential target
for therapy and for early detection.
COLLINS: How does it actually work? How can this be used to
fight breast cancer then?
BERG: Well, if we can target the gene with drugs, then it
could be used in that way to turn the gene off. In fact, in the lab, we have
found several drugs that will do this. In addition, as you may know, the
gene is expressed very highly in the tumors of African- American women. It
is expressed in 89 percent of those tumors, compared with 57 of the tumors
of Caucasian women. So the data may be especially helpful to African-American
women.
COLLINS: And is it true that one of the findings of the study
is that not necessarily is breast cancer more common in African-American
women, but when they do get it, it proves to be more fatal?
BERG: That's exactly right, and reasons for this are not understood.
It is known that social economic factors do play a role, but once those
are taken into account, there is still a differential, and African-American
women die sooner with the same stage of disease.
COLLINS: So the discovery of this gene, then, actually does
provide some new hope for early detection?
BERG: Yes. We're working now with a breast surgeon at George
Washington University to try to develop a blood test for the disease, which
would be much easier than having to have tissue.
COLLINS: And also developing a treatment. What is the next
step as far as the presence of this gene is concerned?
BERG: Well, we're doing a lot of molecular studies in the lab,
so we know something about how this gene acts. It seems to encourage the
growth of cells, and prevent them from dying so that they continue to grow
indefinitely, which is, of course, a signature of a cancer gene, and we are
hoping to develop a pharmaceutical partner who would have the expertise and
knowledge to screen a number of drugs that may be effective.
COLLINS: All right. Dr. Patricia Berg, I'm sure this is a
very exciting find for you, being a researcher...
BERG: Yes, it is.
COLLINS: ... on this case and this study. All right. Excellent
work. Thanks so much. Dr. Patricia Berg, associate professor of biochemistry
and molecular biology.
BERG: Thank you.
RACIAL DISPARITY IN BREAST CANCER
April 21, 2003
CBS News
![]() Breast cancer isn't as common among black women as white women, yet black patients are more likely to die of their disease. Only part of the problem is socioeconomic.
� Interactive: � Links: � Other resources:
|
(AP) Researchers investigating
a gene that they suspect helps spur breast cancer found an unusual racial
disparity: The gene appears active more often in the tumors of black women
than white women.
Breast cancer isn't as common among black women as white women, yet black patients are more likely to die of their disease. Only part of the problem is socioeconomic. Specialists now agree that breast cancer seems more aggressive in black women, although they can't explain why. The new study of the gene called BP1 provides a promising lead, said chief researcher Dr. Patricia Berg of George Washington University Medical Center, whose findings will be published Tuesday by the journal Breast Cancer Research. Berg first discovered that BP1 was active in numerous patients with a type of leukemia. Her research suggested that when the gene is switched on, it interferes with cell regulation in a way that helps cancerous cells survive. Wondering if BP1 played a role in other malignancies, she tested breast cancer tissue from 46 patients. Berg found BP1 activity in 89 percent of the tumors from black women, compared with 57 percent of the white women's tumors. Berg found BP1 expression in only one of seven samples of normal breast tissue. Another surprise: BP1 was active in 100 percent of tumors that are hard to treat because they are not affected by estrogen, compared with three-fourths of estrogen-sensitive tumors. Other cancer specialists called the findings intriguing, but cautioned that the study was far too small to determine if BP1 really plays a role in breast cancer, particularly the racial disparity. "This may be a tip-off, but it's too early to tell," said Dr. Herman Kattlove of the American Cancer Society. Another question is just what role BP1 plays in overall cancer development, said Dr. Joseph Fontana of Wayne State University - noting that Berg also found BP1 activity in two benign breast tumors. Berg plans additional testing to see how often BP1 activity is detected in non-cancerous breast tissue, and is working to develop a blood test. |
Dr. Patricia Berg
Scientists have discovered a breast cancer gene, a finding that
may allow the early detection of the deadly disease and could lead to new
treatments.
Biologist Patricia Berg at George Washington University says
her team has found a gene, called BP1, that was activated in 80 percent of
the breast tumors they studied.
"We actually were surprised at the fact that 80 percent of
women's breast tumors were BP1 positive," she said. "Which is an extremely
high number. And we do think this is an early significant finding."
Speaking at a news conference at George Washington University,
Ms. Berg cautions that her findings are just the first step. Other scientists
will need to confirm them.
But her boss, department head Allan Goldstein of the George
Washington University Medical Center says, if her findings hold up, "Her
team has in effect discovered what may turn out to be the face of the enemy."
Breast cancer is the most common form of cancer among women
worldwide, claiming the lives of nearly 375,000 women each year.
Ms. Berg says she hopes her findings will help to develop a
blood test that will allow doctors to detect breast cancer early. Doctors
say early detection is the key to surviving cancer.
Ms. Berg says researchers can also begin to study drugs already
in the works that act on BP1 that look promising in the laboratory.
Ms. Berg's team had earlier found the gene turned on in patients
with blood cancer, or leukemia. They found the gene was involved in regulating
how cells grow. Since cancer is essentially unchecked cell growth, Ms. Berg
said, "We reasoned that maybe it may be involved in other kinds of cancer
as well as leukemia. We decided to look at breast cancer first. And lo
and behold, there it was."
The hardest-to-treat breast cancer tumors turned out to be
the most likely to have the BP1 gene switched on.
Two in five breast cancer patients have these kinds of tumors.
They are called estrogen-receptor-negative, or ER-negative, tumors.
All of the ER-negative tumors Ms. Berg's team studied had the
BP1 gene turned on. The gene was also switched on in three quarters of the
other kind of breast cancer tumors, ER-positive tumors.
African-American breast cancer patients were more likely than
caucasians to have the BP1 gene switched on. Studies show African-American
women are less likely to survive breast cancer than caucasian women. According
to Ms. Berg, one part of the reason is socioeconomic.
"But it has been speculated that it might be due to a genetic
factor, and so this is a possible candidate," she said.
Ms. Berg added that, as a scientist, and a mother of a daughter,
she hopes the findings can make a real difference in dealing with breast cancer.
Because BP1 is expressed abnormally in breast tumors,
it could provide a useful target for therapy. -- DR. PATRICIA BERG
George Washington University Medical Center |
[Reuters] WASHINGTON, April 22 -- U.S. researchers said Tuesday
they had found a new gene linked with breast cancer that could lead to
new treatments and help explain why black women are more likely to die
from breast cancer than whites.
The gene, called BP1, was found in 80 percent of the samples
of tissue from breast cancer patients, the researchers reported in the June
issue of the journal Breast Cancer Research.
"We are hoping our results will be especially helpful for African-American
women," Dr. Patricia Berg of the George Washington University Medical Center,
who led the study, said in a telephone interview.
While just 57 percent of samples from white breast cancer patients
tested positive for the gene, 89 percent from black women did, the researchers
said.
"Because BP1 is expressed abnormally in breast tumors, it could
provide a useful target for therapy," Berg's team wrote.
Berg noted her team tested only 46 samples, but she said the
percentages were consistent. Of the nine normal breast samples she has tested,
only one has shown "expression' or activation of the BP1 gene.
She also only tested ductal cancer -- but ductal cancer makes
up 80 percent of malignant cancers.
Berg said that like some other genes linked with cancer, BP1
was activated early in the development of an embryo and turned off later.
The gene activates other genes. It is known as a transcription factor. "This type of gene
makes a protein that is like a policeman directing traffic and turns on
and turns off other genes," she said.
Her team will now try to find out what those other genes are.
Berg found earlier that BP1 was active in leukemia, particularly
a form called acute myeloid leukemia. In AML patients it was very active
in children.
A leukemia drug called all-trans-retinoic acid seemed to deactivate
BP1 in lab dishes, Berg said -- showing there was a potential for a drug
targeting the gene.
"What we want to do is discover whether this gene will be useful
for the early detection and treatment of breast cancer," Berg said.
"We found that the gene is active in all three grades of breast
tumors, from the earliest to the most advanced. That means it is activated
quite early in the process and potentially might be good for early detection."
She said she was working with a colleague to try to develop such a test.
In a potential lucky piece of news, all the estrogen receptor
negative tumors tested positive for the BP1 gene, the researchers said.
Breast cancers fall into two categories -- those that respond
to anti-estrogen therapy and those that do not. So-called ER-positive tumors
are easier to treat and respond to such popular drugs as tamoxifen.
ER-negative tumors, which make up 40 percent of breast cancers,
do not. BP1 might offer a new avenue for treating such tumors, Berg's team
said.
Black women in the United States are more likely to have
ER-negative tumors, researchers have found, and are also more likely to
die of breast cancer even when they get similar treatment to white women.
More than 1.2 million women worldwide will develop breast cancer
this year -- 200,000 in the United States. In the United States, 40,000
will die of breast cancer in 2003, according to the American Cancer Society.
NEW GENE ACTIVE IN 80 PERCENT OF BREAST CANCER PATIENTS,
GWU-PATRICIA BERG TEAM REPORTS; TARGET FOR EARLY DETECTION AND THERAPY
To: National Desk, Photo Editor
Contact: Bob Weiner, 301-283-0821 for Dr. Patricia Berg
Barbara Porter of the George Washington University Medical Center, 202-994-3121
April 22, 2003
WASHINGTON, April 18 /U.S. Newswire/ -- The following was released today by George Washington University Medical Center:
-- Gene Active in 80 Pct. of Breast Cancer Patients, GWU-Patricia Berg Team Reports; Target for Early Detection and Therapy
--While Overall Impact, More African-American Breast Cancer Patients Express Gene and Could be Helped by Findings
A George Washington University Medical Center team, led by Dr. Patricia Berg, has found that a new gene, BP1, discovered and cloned by Dr. Berg, is expressed in 80 percent of breast cancer patients in preliminary findings. Dr. Berg, Associate Professor of Biochemistry and Molecular Biology, stated, "Because of these high numbers and our molecular studies, we believe that this gene may offer a useful new early target for breast cancer detection and therapy, and we must now conduct expedited research." Dr. Berg has been studying the gene for 16 years, and began breast cancer testing in 1999 when she joined the faculty of GWU.
The GWU/Berg team also reported that "While the research into BP1 may impact all groups with breast cancer in that there was an overall higher expression rate, the findings may prove especially helpful to African-Americans, who disproportionately expressed the new gene." The rate of expression or "activation" for Caucasian women with breast cancer was 57 percent. Among African-American women, it was 89 percent.
Team members held a news conference today at GWUMC to report their
findings, published in the journal "Breast Cancer Research", available
11:00 AM EDT today on-line at:
http://breast-cancer-research.com/content/5/4/R82
prior to printing of the June edition.
In addition to GWU, the authors of the paper included scientists from Children's National Medical Center, the University of Maryland Medical School, and Howard University College of Medicine.
Dr. Berg pointed to more than 1.2 million people diagnosed with breast cancer annually, including over 212,000 in the U.S., and stated, "We hope that this kind of research can make a real difference in addressing a major disease. 40,000 American women died from breast cancer last year alone." Dr. Berg asserted that the discovery, cloning, and findings of the effect of the new gene "could now expedite research to put us further on the trail of treating breast cancer and other cancers." Berg has previously published studies demonstrating that BP1 is also expressed in patients with leukemia. BP1 is a newly discovered form of a previously known gene, DLX4.
Dr. Allan Goldstein, Chairman of the GWU Medical Center Department of Biochemistry and Molecular Biology, stated, "Dr. Berg's research is cutting edge and is exactly the reason we brought her to GWU. These findings are the fruits of over fifteen years of research by Dr. Berg. The results are both important and exciting in terms of potential clinical application.
Prior to GWU, Dr. Berg was on the faculty of the University of Maryland Medical School and was a Senior Staff Fellow at the National Institutes of Health.
Source: Robert Weiner Associates and George Washington University Medical Center
--- EDITOR'S NOTE: A high-resolution, publication-ready photo supporting
this story is available for free editorial use at
http://www.wirepix.com/newsphotos/USN
|
|||
|
|
|
|
|
![]() |
|
Sorted by date |
New gene linked to breast cancer
Daily Times, Pakistan - Apr
27, 2003
... especially helpful for African-American women,�
Dr. Patricia Berg of the George
Washington University ... While just
57 percent of samples from white breast ...
Gene activated in 80% of breast cancer patients
EurekAlert, DC - Apr 25, 2003
A George Washington University Medical
Center team, led by Patricia Berg, has
discovered that the gene BP1 is activated in 80% of breastcancer
patients. ...
Possible
gene target for breast cancer patients
Health-News.co.uk, U.K. - Apr
24, 2003
... have identified a gene that could be a new target
for breast cancer ... ductal breast
tumours investigated by the team, led by Dr PatriciaBerg
of the George ...
New Tumor
Hope
New York Post, NY - Apr 24,
2003
... A team of researchers at George WashingtonUniversity
in ... a gene, called BP1, in 80
percent of breast-cancer ... this is
an early significant finding," Dr. Patricia ...
Newly-Discovered Gene Linked to Breast Cancer
Voice of America - Apr 23,
2003
... University Medical Center in Washington,
DC say the gene, called BP-1, is active
in 80 percent of breast cancer patients they
studied. Dr. Patricia Berg, who ...
New Gene Linked with Breast Cancer
Yahoo News - Apr 23, 2003
... especially helpful for African-American women,"
Dr. Patricia Berg of the George
Washington University ... While just
57 percent of samples from white breast ...
New Gene Linked with Breast Cancer
Yahoo News - Apr 23, 2003
... especially helpful for African-American women,"
Dr. Patricia Berg of the George
Washington University ... While just
57 percent of samples from white breast ...
New gene may provide cancer cure links
Independent Online, South Africa
- Apr 23, 2003
... be especially helpful for African-American women,"
Dr Patricia Berg of the George
Washington University ... While just
57 percent of samples from white breast ...
New gene may provide cancer cure links
Independent Online, South Africa
- Apr 23, 2003
... be especially helpful for African-American women,"
Dr Patricia Berg of the George
Washington University ... While just
57 percent of samples from white breast ...
New
gene linked with breast cancer found
Hindustan Times, India - Apr
23, 2003
... will be especially helpful for African-American
women," Dr Patricia Berg of the George
Washington University ... just 57 per
cent of samples from white breast ...
Researchers probe gene linked to breast cancer
Billings Gazette, MT - Apr
23, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Gene
finding gives hope for breast-cancer cure
Washington Times, DC - Apr
22, 2003
A team of researchers at the George Washington
University ... gene is active in 80 percent
of breast-cancer ... The team, led by
the gene's discoverer, Dr. Patricia ...
Scientists Make Key Finding in Link to Breast Cancer
Voice of America - Apr 22,
2003
A university biologist in Washington DC, Patricia
Berg ... A colleague of Ms. Berg's
at George Washington University ...
Forty percent of breast cancer patients have ...
Gene discovery explains cancer's racism
ABC Online, Australia - Apr
22, 2003
... Dr Patricia Berg of the George
Washington University Medical Centre, who led the
study, said. While just 57 per cent of samples from white
breast cancer ...
New gene linked
with breast cancer
ABC Online, Australia - Apr
22, 2003
... Dr Patricia Berg of the George
Washington University Medical Centre, who led the
study, said. While just 57 per cent of samples from white
breast cancer ...
New gene linked with breast cancer
ABC Online, Australia - Apr
22, 2003
... Dr. Patricia Berg of the George
Washington University Medical Centre, who led
the study, said. While just 57 per cent of samples from
white breast cancer ...
Researchers Find Gene Linked to Breast Cancer
Voice of America - Apr 22,
2003
Scientists have discovered a breast cancer
gene, a finding that may allow the early
detection of the deadly disease and ... Biologist
Patricia Berg at George ...
New Gene Linked with Breast Cancer
Yahoo News - Apr 22, 2003
... especially helpful for African-American women,"
Dr. Patricia Berg of the George
Washington University ... While just
57 percent of samples from white breast ...
Study
Links Gene To Breast Cancer
WCVB-TV, MA - Apr 22, 2003
... study, Dr. Patricia Berg, a researcher
at George Washington University, found BP-1
was active -- or turned on -- in 80 percent of women with
breast cancer. ...
New gene linked with
breast cancer
MSNBC - Apr 22, 2003
... especially helpful for African-American women,�
Dr. Patricia Berg of the George
Washington University ... While just
57 percent of samples from white breast ...
New Gene Linked to Breast Cancer
Yahoo News - Apr 22, 2003
... especially helpful for African-American women,"
Dr. Patricia Berg of the George
Washington University ... While just
57 percent of samples from white breast ...
New Gene Linked to Breast Cancer
Reuters, UK - Apr 22, 2003
... especially helpful for African-American women,"
Dr. Patricia Berg of the George
Washington University ... While just
57 percent of samples from white breast ...
New Gene Linked to Breast Cancer
Yahoo News - Apr 22, 2003
... especially helpful for African-American women,"
Dr. Patricia Berg of the George
Washington University ... While just
57 percent of samples from white breast ...
New Gene Linked with Breast Cancer
Yahoo News - Apr 22, 2003
... especially helpful for African-American women,"
Dr. Patricia Berg of the George
Washington University ... While just
57 percent of samples from white breast ...
New Gene Linked with Breast Cancer
Yahoo News - Apr 22, 2003
... especially helpful for African-American women,"
Dr. Patricia Berg of the George
Washington University ... While just
57 percent of samples from white breast ...
New gene
linked with breast cancer
Reuters AlertNet, UK - Apr
22, 2003
... especially helpful for African-American women,"
Dr. Patricia Berg of the George
Washington University ... While just
57 percent of samples from white breast ...
New Gene Linked with Breast Cancer
Yahoo News - Apr 22, 2003
... especially helpful for African-American women,"
Dr. Patricia Berg of the George
Washington University ... While just
57 percent of samples from white breast ...
New Gene Linked with Breast Cancer
Yahoo News - Apr 22, 2003
... especially helpful for African-American women,"
Dr. Patricia Berg of the George
Washington University ... While just
57 percent of samples from white breast ...
New Gene Linked with Breast Cancer
Reuters, UK - Apr 22, 2003
... especially helpful for African-American women,"
Dr. Patricia Berg of the George
Washington University ... While just
57 percent of samples from white breast ...
Gene may provide breast cancer clues
CNN - Apr 22, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Researchers Probe Gene Possibly Linked to Breast Cancer
Washington Post, DC - Apr 22,
2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Gene possibly linked to breast cancer more active in black
women ...
Canoe News, Canada - Apr 22,
2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Mentally
ill children forced into care of state for help
Seattle Post Intelligencer, WA
- Apr 22, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published today by the journal Breast
Cancer Research. ...
Scientists find racial disparity while probing cancer gene
Inland Valley Daily Bulletin, CA
- Apr 22, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Racial Disparity In Breast Cancer
CBS News - Apr 21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Race Cited in Breast Cancer Gene Study
Washington Post, DC - Apr 21,
2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Breast cancer gene study finds racial disparity
CTV, Canada - Apr 21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Researchers probe gene possibly linked to breast cancer
USA Today - Apr 21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Researchers
Probe Gene Possibly Linked to Breast Cancer
KTUL, OK - Apr 21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Researchers probe gene possibly linked to breast cancer
Billings Gazette, MT - Apr
21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Race Cited in Breast Cancer Gene Study
Newsday - Apr 21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Race Cited in
Breast Cancer Gene Study
Akron Beacon Journal, OH -
Apr 21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Race Cited
in Breast Cancer Gene Study
Belleville News-Democrat, IL
- Apr 21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Race Cited in Breast Cancer Gene Study
Biloxi Sun Herald, MS - Apr
21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Race Cited in Breast Cancer Gene Study
Wilkes Barre Weekender, PA
- Apr 21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Race Cited in Breast Cancer Gene Study
Newsday - Apr 21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Race Cited in Breast Cancer Gene Study
Duluth News Tribune, MN - Apr
21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Race Cited in Breast Cancer Gene Study
Aberdeen American News, SD
- Apr 21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Race Cited
in Breast Cancer Gene Study
Wichita Eagle, KS - Apr 21,
2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Race Cited in Breast Cancer Gene Study
Fort Wayne Journal Gazette, IN
- Apr 21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Race Cited
in Breast Cancer Gene Study
ABC News - Apr 21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Race Cited in
Breast Cancer Gene Study
Macon Telegraph, GA - Apr 21,
2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Race Cited in Breast Cancer Gene Study
Centre Daily Times, PA - Apr
21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Race Cited in Breast Cancer Gene Study
Kansas City Star, MO - Apr
21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Researchers
Probe Gene Possibly Linked to Breast Cancer
WSET, VA - Apr 21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Race Cited in Breast Cancer Gene Study
Sarasota Herald-Tribune, FL
- Apr 21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Race Cited in Breast Cancer Gene Study
Yahoo News - Apr 21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Race Cited in Breast Cancer Gene Study
Columbus Ledger-Enquirer, GA
- Apr 21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...
Race
Cited in Breast Cancer Gene Study
Grand Forks Herald, ND - Apr
21, 2003
... researcher Dr. Patricia Berg of
George Washington University Medical Center, whose
findings will be published Tuesday by the journal Breast
Cancer Research. ...